Standards in semen examination: publishing reproducible and reliable data based on high-quality methodology

Hum Reprod 2022 37(11):2497-2502

Lars Björndahl 1 , Christopher L R Barratt 2 , David Mortimer 3 , Ashok Agarwal 4 , Robert J Aitken 5 , Juan G Alvarez 6 7 , Natalie Aneck-Hahn 8 , Stefan Arver 1 , Elisabetta Baldi 9 , Lluís Bassas 10 , Florence Boitrelle 11 12 , Riana Bornman 13 , Douglas T Carrell 14 15 , José A Castilla 16 17 , Gerardo Cerezo Parra 18 , Jerome H Check 19 20 , Patricia S Cuasnicu 21 , Sally Perreault Darney 22 23 , Christiaan de Jager 24 , Christopher J De Jonge 25 , Joël R Drevet 26 , Erma Z Drobnis 27 , Stefan S Du Plessis 28 , Michael L Eisenberg 29 30 , Sandro C Esteves 31 32 33 , Evangelini A Evgeni 34 35 , Alberto Ferlin 36 , Nicolas Garrido 37 , Aleksander Giwercman 38 , Ilse G F Goovaerts 39 , Trine B Haugen 40 , Ralf Henkel 41 42 , Lars Henningsohn 43 44 , Marie-Claude Hofmann 45 , James M Hotaling 46 , Piotr Jedrzejczak 47 , Pierre Jouannet 48 , Niels Jørgensen 49 50 , Jackson C Kirkman Brown 51 52 53 , Csilla Krausz 54 , Maciej Kurpisz 55 , Ulrik Kvist 1 , Dolores J Lamb 56 , Hagai Levine 57 , Kate L Loveland 58 , Robert I McLachlan 59 , Ali Mahran 60 61 , Liana Maree 42 , Sarah Martins da Silva 2 , Michael T Mbizvo 62 , Andreas Meinhardt 63 , Roelof Menkveld 64 , Sharon T Mortimer 3 65 , Sergey Moskovtsev 66 67 , Charles H Muller 68 , Maria José Munuce 69 , Monica Muratori 54 , Craig Niederberger 70 71 , Cristian O'Flaherty 72 , Rafael Oliva 73 74 , Willem Ombelet 75 76 , Allan A Pacey 77 78 , Michael A Palladino 79 , Ranjith Ramasamy 80 , Liliana Ramos 81 , Nathalie Rives 82 , Eduardo Rs Roldan 83 , Susan Rothmann 84 , Denny Sakkas 85 , Andrea Salonia 86 87 , Maria Cristina Sánchez-Pozo 88 , Rosanna Sapiro 89 , Stefan Schlatt 90 , Peter N Schlegel 91 , Hans-Christian Schuppe 92 , Rupin Shah 93 , Niels E Skakkebæk 49 , Katja Teerds 94 , Igor Toskin 95 , Herman Tournaye 96 , Paul J Turek 97 , Gerhard van der Horst 98 99 100 , Monica Vazquez-Levin 101 , Christina Wang 102 103 , Alex Wetzels 104 , Theodosia Zeginiadou 105 106 , Armand Zini 107

1 ANOVA, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden. 2 Reproductive Medicine Research Group, Division of Systems Medicine, School of Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK. 3 Oozoa Biomedical Inc., West Vancouver, BC, Canada. 4 Case Western Reserve University, Moreland Hills, OH, USA. 5 Priority Research Centre for Reproductive Science, Faculty of Science and Faculty of Health & Medicine, University of Newcastle, Callaghan, NSW, Australia. 6 Centro Androgen, La Coruña, Spain. 7 Harvard Medical School, Boston, MA, USA. 8 Department of Urology, University of Pretoria, Pretoria, South Africa. 9 Department of Experimental and Clinical Medicine, University of Florence, Florence, Tuscany, Italia. 10 Andrology Department, Laboratory of Andrology and Sperm Bank, Fundació Puigvert, Barcelona, Spain. 11 Department of Reproductive Biology, Fertility Preservation, Andrology, CECOS, Poissy Hospital, Poissy, France. 12 Paris Saclay University, UVSQ, INRAE, BREED, Jouy-en-Josas, France. 13 School of Health Systems and Public Health, University of Pretoria, Pretoria, South Africa. 14 Andrology and IVF Laboratory, Division of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA. 15 Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT, USA. 16 GAMETIA Biobank, Granada, Spain. 17 Hospital Universitario Virgen de las Nieves and Instituto de Investigación Biosanitaria ibs. GRANADA, Granada, Spain. 18 LAFER Sperm Bank, Tuxpan 10-606, Roma Sur, C.P. 06760, Cuauhtémoc, Mexico City, Mexico. 19 Robert Wood Johnson Medical School at Camden, The University of Medicine and Dentistry of New Jersey, Camden, NJ, USA. 20 Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Cooper Hospital/University Medical Center, Melrose Park, PA, USA. 21 Instituto de Biología y Medicina Experimental (IbyME-CONICET), Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina. 22 US EPA, Cary, NC, USA. 23 US NIH, Cary, NC, USA. 24 Faculty of Health Science, University of Pretoria, Pretoria, South Africa. 25 University of Minnesota Medical Center, University of Minnesota, Minneapolis, MN, USA. 26 Université Clermont Auvergne/CNRS/INSERM-GreD Institute, Clermont-Ferrand, France. 27 School of Medicine, University of Missouri, Columbia, MI, USA. 28 College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates. 29 Male Reproductive Medicine and Surgery, Stanford University School of Medicine, Stanford, CA, USA. 30 Department of Urology, Stanford University School of Medicine, Stanford, CA, USA. 31 ANDROFERT, Andrology and Human Reproduction Clinic, Campinas, Brazil. 32 Department of Surgery (Division of Urology), University of Campinas (UNICAMP), Campinas, Brazil. 33 Faculty of Health, Aarhus University, Aarhus C, Denmark. 34 CRYOGONIA Cryopreservation Bank, Athens, Greece. 35 Laboratory of Physiology, Department of Medicine, Democritus University of Thrace, Greece. 36 Unit of Andrology and Reproductive Medicine, Department of Medicine, University of Padova, Padova, Italia. 37 IVI Foundation, Health Research Institute La Fe, Valencia, Spain. 38 Department of Translational Medicine, Lund University, Malmö, Sweden. 39 Antwerp University Hospital, Edegem, Belgium. 40 Department of Life Sciences and Health, Oslo Metropolitan University, Oslo, Norway. 41 Department of Metabolism, Digestion & Reproduction, Imperial College London, London, UK. 42 Department of Medical Bioscience, University of the Western Cape, Bellville, South Africa. 43 Division of Urology, Department of CLINTEC, Karolinska Institutet, Stockholm, Sweden. 44 Department of Urology, Karolinska University Hospital, Stockholm, Sweden. 45 Department of Endocrine Neoplasia & Hormonal Disorders, University of Texas MD Anderson Cancer Center, Houston, TX, USA. 46 Division of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA. 47 Department of Cell Biology, Poznan University of Medical Science, Poznan, Poland. 48 Université Paris Descartes, Paris, France. 49 Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. 50 International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. 51 Centre for Human Reproductive Science (ChRS), UK. 52 College of Medical & Dental Sciences, University of Birmingham, UK. 53 Birmingham Women's and Children's NHS Foundation Trust, UK. 54 Department of Biomedical, Experimental and Clinical Sciences "Mario Serio", University of Florence, Florence, Italy. 55 Department of Reproductive Biology and Stem Cells, Institutet of Human Genetics, Poznan, Poland. 56 Brady Department of Urology, Center for Reproductive Genomics and Englander Institute for Precision Medicine, Weill Cornell Medical College, Cornell University, New York, NY, USA. 57 Braun School of Public Health and Community Medicine, Hadassah Medical Center, The Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel. 58 Hudson Institute, Centre for Reproductive Health, Monash University, Clayton, VIC, Australia. 59 Hudson Institute of Medical Research, Centre for Endocrinology and Metabolism, Monash University, Clayton, VIC, Australia. 60 Dermatology and Andrology Department, Assiut University Hospital, Assiut, Egypt. 61 Faculty of Medicine, Assiut University, Assiut, Egypt. 62 Country Director, Population Council (International Programs). 63 Department of Anatomy and Cell Biology, Justus-Liebig-University of Giessen, Giessen, Germany. 64 Department of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa. 65 Division of REI, Department of Obstetrics & Gynaecology, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada. 66 Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, ON, Canada. 67 CreATe Fertility Centre, Toronto, ON, Canada. 68 Male Fertility Laboratory, Department of Urology, University of Washington School of Medicine, Seattle, WA, USA. 69 Laboratorio de Medicina Reproductiva, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Argentina. 70 Department of Urology, UIC College of Medicine, IL, USA. 71 Department of Bioengineering, UIC College of Engineering, IL, USA. 72 Department of Surgery (Urology Division), McGill University, Montréal, QC, Canada. 73 Molecular Biology of Reproduction and Development Group, Biomedical Research Institute August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain. 74 Hospital Clínic, University of Barcelona, Barcelona, Spain. 75 Genk Institute for Fertility Technology, Genk, Belgium. 76 Department of Obstetrics and Gynaecology, ZOL Hospitals and Hasselt University, Genk, Belgium. 77 Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK. 78 Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK. 79 Bloomfield College, Bloomfield, NJ, USA. 80 Department of Urology, Miller School of Medicine, University of Miami, Miami, FL, USA. 81 Division of Reproductive Medicine, Department of Obstetrics and Gynaecologie, Radboud UMC, Nijmegen, The Netherlands. 82 Service Laboratoire de Biologie de la Reproduction-CECOS, Equipe Physiopathologie Surrénalienne et Gonadique, Unité Inserm 1239 NorDic, CHU-Hôpitaux de Rouen, UFR Santé-Université de Rouen, Rouen, France. 83 Department of Biodiversity and Evolutionary Biology, Museo Nacional de Ciencias Naturales (CSIC), Madrid, Spain. 84 Fertility Solutions Inc., Warrensville Heights, OH, USA. 85 Boston IVF, Boston, MA, USA. 86 University Vita-Salute San Raffaele, Milan, Italy. 87 Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy. 88 Department of Clinical Chemistry and Molecular Biology, Virgen del Rocío University Hospital, Seville, Spain. 89 Depto de Histologia y Embriología, Facultad de Medicina, Gral. Flores, Uruguay. 90 Centre of Reproductive Medicine and Andrology, Münster, Germany. 91 Department of Urology, Weill Cornell Medicine, New York, NY, USA. 92 Section of Andrology, Department of Urology, Pediatric Urology & Andrology, Justus-Liebig-University/University Hospital of Giessen-Marburg, Giessen, Germany. 93 Lilavati Hospital & Research Centre, Mumbai, India. 94 Human and Animal Physiology, Wageningen University, Wageningen, The Netherlands. 95 WHO Department of Sexual and Reproductive Health and Research (includes the UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction-HRP), Geneva, Switzerland. 96 Centre for Reproductive Medicine, Vrije Universiteit Brussel, Brussels, Belgium. 97 The Turek Clinic, San Francisco, CA, USA. 98 Medical Bioscience, University of the Western Cape, Bellville, South Africa. 99 Physiology Medical School, Stellenbosch University, Stellenbosch, South Africa. 100 Department of Animal Science, Stellenbosch University, Stellenbosch, South Africa. 101 IBYME, CONICET-FIBYME, Buenos Aires, Argentina. 102 Clinical and Translational Science Institute, The Lundquist Institute, Torrance, CA, USA. 103 Division of Endocrinology, Department of Medicine, Harbor-UCLA Medical Center, Torrance, CA, USA. 104 Fertility Laboratory, Radboud University Medical Centre, Nijmegen, The Netherlands. 105 Thessaloniki Andrology Laboratory-Hellenic Sperm Bank, Thessaloniki, Greece. 106 Laboratory of Histology-Embryology, Medical School, University of Athens, Athens, Greece. 107 Division of Urology, Department of Surgery, St Mary's Hospital, McGill University, Montreal, Canada.

DOI: 10.1093/humrep/deac189
PMID: 36112046
Pubmed: https://pubmed.ncbi.nlm.nih.gov/36112046
Texto completo: https://academic.oup.com/humrep/article-lookup/doi/10.1093/humrep/deac189

Abstract:
Biomedical science is rapidly developing in terms of more transparency, openness and reproducibility of scientific publications. This is even more important for all studies that are based on results from basic semen examination. Recently two concordant documents have been published: the 6th edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen, and the International Standard ISO 23162:2021. With these tools, we propose that authors should be instructed to follow these laboratory methods in order to publish studies in peer-reviewed journals, preferable by using a checklist as suggested in an Appendix to this article.