PUBLICACIONES DE INTEGRANTES DEL DEPARTAMENTO

AÑO 2010

Barbeito AG, Martinez-Palma L, Vargas MR, Pehar M, Mañay N, Beckman JS, Barbeito L, Cassina P .
Lead exposure stimulates VEGF expression in the spinal cord and extends survival in a mouse model of ALS.
Neurobiol Dis. 2010 Mar;37(3):574-80.
Bartesaghi S, Wenzel J, Trujillo M, López M, Joseph J, Kalyanaraman B, Radi R.
Lipid peroxyl radicals mediate tyrosine dimerization and nitration in membranes.
Chem Res Toxicol. 2010 Apr 19;23(4):821-35.
Gandelman M, Peluffo H, Beckman JS, Cassina P, Barbeito L.
Extracellular ATP and the P2X(7) receptor in astrocyte-mediated motor neuron death: implications for amyotrophic lateral sclerosis.
J Neuroinflammation. 2010 Jun 9;7:33.
Pouso P, Quintana L, Bolatto C, Silva AC.
Brain androgen receptor expression correlates with seasonal changes in the behavior of a weakly electric fish, Brachyhypopomus gauderio.
Horm Behav. 2010 Aug 3.
Skowronek MF, Alciaturi J, Casanova G, Capurro A, Montes JM, Sapiro R .
Value of quantitative ultramorphological sperm analysis in infertile men.
Reprod Biol. 2010 Jul;10(2):125-39.

AÑO 2009

Anesetti G, Lombide P, Chávez-Genaro R.
Prepubertal estrogen exposure modifies neurotrophin receptor expression in celiac neurons and alters ovarian innervation.
Auton Neurosci. 2009 Jan 28;145(1-2):35-43.

Gonzalez P, Burgaya F, Acarin L, Peluffo H, Castellano B, Gonzalez B.
Interleukin-10 and interleukin-10 receptor-I are upregulated in glial cells after an excitotoxic injury to the postnatal rat brain.
J Neuropathol Exp Neurol. 2009 Apr;68(4):391-403.

Irigoín F, Inada NM, Fernandes MP, Piacenza L, Gadelha FR, Vercesi AE, Radi R.
Mitochondrial calcium overload triggers complement-dependent superoxide-mediated programmed cell death in Trypanosoma cruzi.
Biochem J. 2009 Mar 15;418(3):595-604.

Marichal N, García G, Radmilovich M, Trujillo-Cenóz O, Russo RE.
Enigmatic central canal contacting cells: immature neurons in "standby mode"?
J Neurosci. 2009 Aug 12;29(32):10010-24.

Olivera S, Fernandez A, Latini A, Rosillo JC, Casanova G, Wajner M, Cassina P, Barbeito L.

Astrocytic proliferation and mitochondrial dysfunction induced by accumulated glutaric acidemia I (GAI) metabolites: possible implications for GAI pathogenesis.

Neurobiol Dis. 2008 Dec;32(3):528-34.


Sotelo-Silveira JR, Lepanto P, Elizondo MV, Horjales S, Palacios F, Martinez Palma L, Marin M, Beckman JS, Barbeito L.< o:p>
Axonal mitochondrial clusters containing mutant SOD1 in transgenic models of ALS.
Antioxid Redox Signal. 2009 Apr 3.



AÑO 2008

Bartesaghi S, Peluffo G, Zhang H, Joseph J, Kalyanaraman B, Radi R.
Chapter 12 Tyrosine Nitration, Dimerization, and Hydroxylation by Peroxynitrite in Membranes as Studied by the Hydrophobic Probe N-t-BOC-l-tyrosine tert-Butyl Ester.
Methods Enzymol. 2008;441C:217-236.

Breijo M, Anesetti G, Martínez L, Sim RB, Ferreira AM.
Echinococcus granulosus: the establishment of the metacestode is associated with control of complement-mediated early inflammation.
Exp Parasitol. 2008 Feb;118(2):188-96. Epub 2007 Aug 23.< o:p>

Cassina P, Cassina A, Pehar M, Castellanos R, Gandelman M, de León A, Robinson KM, Mason RP, Beckman JS, Barbeito L, Radi R.
Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants.
J Neurosci. 2008 Apr 16;28(16):4115-22.

Dupuis L, Pehar M, Cassina P, Rene F, Castellanos R, Rouaux C, Gandelman M, Dimou L, Schwab ME, Loeffler JP, Barbeito L, Gonzalez de Aguilar JL.
Nogo receptor antagonizes p75NTR-dependent motor neuron death.
Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):740-5. Epub 2008 Jan 8.< o:p>

Irigoín F, Cibils L, Comini MA, Wilkinson SR, Flohé L, Radi R.
Insights into the redox biology of Trypanosoma cruzi: Trypanothione metabolism and oxidant detoxification.
Free Radic Biol Med. 2008 Jun 12. < o:p>

Olivera S, Fernandez A, Latini A, Rosillo JC, Casanova G, Wajner M, Cassina P, Barbeito L.< o:p>
Astrocytic proliferation and mitochondrial dysfunction induced by accumulated glutaric acidemia I (GAI) metabolites: possible implications for GAI pathogenesis.
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Neurobiol Dis. 2008 Dec;32(3):528-34. < o:p>

Pastenes L, Ibáñez F, Bolatto C, Pavéz L, Cambiazo V.
Molecular characterization of a novel patched-related protein in Apis mellifera and Drosophila melanogaster.
Arch Insect Biochem Physiol. 2008 Jul;68(3):156-70.< o:p>

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Rey G, Skowronek F, Alciaturi J, Alonso J, Bertoni B, Sapiro R.
Toll receptor 4 Asp299Gly polymorphism and its association with preterm birth and premature rupture of membranes in a South American population.
Mol Hum Reprod. 2008 Sep;14(9):555-9
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Russo RE, Reali C, Radmilovich M, Fernández A, Trujillo-Cenóz O.
Connexin 43 delimits functional domains of neurogenic precursors in the spinal cord.
J Neurosci. 2008 Mar 26;28(13):3298-309.< o:p>

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AÑO 2007

Castello ME, Nogueira J, Trujillo-Cenoz O, Caputi AA.
Sensory processing in the fast electrosensory pathway of pulse gymnotids studied at multiple integrative levels.
Comp Biochem Physiol A Mol Integr Physiol. 2007 Apr 22

Chávez-Genaro R, Lombide P, Domínguez R, Rosas P and Vázquez-Cuevas F
Sympathetic pharmacological denervation in ageing rats: effects on ovulatory response and follicular population
Reproduction, Fertility and Development, 2007, 19, 954–960

Pehar M, Vargas MR, Robinson KM, Cassina P, Diaz-Amarilla PJ, Hagen TM, Radi R, Barbeito L, Beckman JS
.

Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis.
J Neurosci. 2007 Jul 18;27(29):7777-85.

Peluffo H, González P, Arís A, Acarin L, Saura J, Villaverde A, Castellano B, González B.
RGD domains neuroprotect the immature brain by a glial-dependent mechanism.
Ann Neurol. 2007 Sep;62(3):251-61.

Piacenza L, Irigoin F, Alvarez MN, Peluffo G, Taylor MC, Kelly JM, Wilkinson SR, Radi R.
Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase overexpression.
Biochem J. 2007 Apr 15;403(2):323-34.

Trujillo-Cenóz O, Fernández A, Radmilovich M, Reali C, Russo RE.
Cytological organization of the central gelatinosa in the turtle spinal cord.
J Comp Neurol. 2007 May 10;502(2):291-308.

AÑO 2006

Chavez-Genaro R, Lombide P, Anesetti G.
A quantitative study of rat uterine sympathetic innervation during pregnancy and post partum.
Reprod Fertil Dev. 2006;18(5):525-31.

Nogueira J, Castello ME, Caputi AA.
The role of single spiking spherical neurons in a fast sensory pathway.
J Exp Biol. 2006 Mar;209(Pt 6):1122-34.

Pehar M, Cassina P, Vargas MR, Xie Y, Beckman JS, Massa SM, Longo FM, Barbeito L.

Modulation of p75-dependent motor neuron death by a small non-peptidyl mimetic of the neurotrophin loop 1 domain.
Eur J Neurosci. 2006 Sep;24(6):1575-80.
Pehar M, Vargas MR, Robinson KM, Cassina P, England P, Beckman JS, Alzari PM, Barbeito L. 
Peroxynitrite transforms nerve growth factor into an apoptotic factor for motor neurons.

 Free Radic Biol Med. 2006 Dec 1;41(11):1632-44.

Ricart K, J Pearson R Jr, Viera L,
Cassina P, Kamaid A, Carroll SL, Estevez AG.
Interactions between beta-neuregulin and neurotrophins in motor neuron apoptosis.
J Neurochem. 2006 Apr;97(1):222-33.

Vargas MR, Pehar M, Cassina P, Beckman JS, Barbeito L.
Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis.
J Neurochem. 2006 May;97(3):687-96.

Zhang Z, Kostetskii I, Tang W, Haig-Ladewig L, Sapiro R, Wei Z, Patel AM, Bennett J, Gerton GL, Moss SB, Radice GL, Strauss JF 3rd.
Deficiency of SPAG16L causes male infertility associated with impaired sperm motility.
Biol Reprod. 2006 Apr;74(4):751-9.

AÑO 2005


Cassina P, Pehar M, Vargas MR, Castellanos R, Barbeito AG, Estevez AG, Thompson JA, Beckman JS, Barbeito L. Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis.
J Neurochem. 2005 Apr;93(1):38-46.

Pehar M, Vargas MR, Cassina P, Barbeito AG, Beckman JS, Barbeito L.
Complexity of astrocyte-motor neuron interactions in amyotrophic lateral sclerosis.
Neurodegener Dis. 2005;2(3-4):139-46.

Vargas MR, Pehar M, Cassina P, Martinez-Palma L, Thompson JA, Beckman JS, Barbeito L.
Fibroblast growth factor-1 induces heme oxygenase-1 via nuclear factor erythroid 2-related factor 2 (Nrf2) in spinal cord astrocytes: consequences for motor neuron survival.
J Biol Chem. 2005 Jul 8;280(27):25571-9

AÑO 2004

Barbeito LH, Pehar M, Cassina P, Vargas MR, Peluffo H, Viera L, Estevez AG, Beckman JS.
A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis.
Brain Res Brain Res Rev. 2004 Dec;47(1-3):263-74. Review.

Chifflet S, Bolatto C, Tolosa S.
A rapid method for fibronectin purification on nitrocellulose membranes suitable for tissue culture.
J Biochem Biophys Methods. 2004 May 31;59(2):139-43.

Pehar M, Cassina P, Vargas MR, Castellanos R, Viera L, Beckman JS, Estevez AG, Barbeito L.
Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis.
J Neurochem. 2004 Apr;89(2):464-73.

Peluffo H, Shacka JJ, Ricart K, Bisig CG, Martinez-Palma L, Pritsch O, Kamaid A, Eiserich JP, Crow JP, Barbeito L, Estevez AG.
Induction of motor neuron apoptosis by free 3-nitro-L-tyrosine.
J Neurochem. 2004 May;89(3):602-12.

Russo RE, Fernandez A, Reali C, Radmilovich M, Trujillo-Cenoz O.
Functional and molecular clues reveal precursor-like cells and immature neurones in the turtle spinal cord.

J Physiol. 2004 Nov 1;560(Pt 3):831-8.

Sharif A, Renault F, Beuvon F, Castellanos R, Canton B, Barbeito L, Junier MP, Chneiweiss H.
The expression of PEA-15 (phosphoprotein enriched in astrocytes of 15 kDa) defines subpopulations of astrocytes and neurons throughout the adult mouse brain.
Neuroscience. 2004;126(2):263-75.

Vargas MR, Pehar M, Cassina P, Estevez AG, Beckman JS, Barbeito L.
Stimulation of nerve growth factor expression in astrocytes by peroxynitrite.
In Vivo. 2004 May-Jun;18(3):269-74.

AÑO 2003

Bolatto C, Chifflet S, Megighian A, Cantera R.
Synaptic activity modifies the levels of Dorsal and Cactus at the neuromuscular junction of Drosophila.
J Neurobiol. 2003 Feb 15;54(3):525-36.

Caputi AA, Aguilera PA, Castello ME.
Probability and amplitude of novelty responses as a function of the change in contrast of the reafferent image in G carapo.
J Exp Biol. 2003 Mar;206(Pt 6):999-1010.

Chalar C, Richeri A, Viettro L, Chavez-Genaro R, Bianchimano P, Marmol NM, Crutcher K, Burnstock G, Cowen T, Brauer MM. 
Plasticity in developing rat uterine sensory nerves: the role of NGF and TrkA.
Cell Tissue Res. 2003 Nov;314(2):191-205.

Chifflet S, Hernandez JA, Grasso S, Cirillo A.
Nonspecific depolarization of the plasma membrane potential induces cytoskeletal modifications of bovine corneal endothelial cells in culture.
Exp Cell Res. 2003 Jan 1;282(1):1-13.

Martínez-Palma L, Pehar M, Cassina P, Peluffo H, Castellanos R,Anesetti G, Beckman JS, Barbeito L.
Involvement of nitric oxide on kainate-induced toxicity in oligodendrocyte precursors.
Neurotox Res 2003 5(6):399-406

Radmilovich M, Fernandez A, Trujillo-Cenoz O.
Environment temperature affects cell proliferation in the spinal cord and brain of juvenile turtles.
J Exp Biol. 2003 Sep;206(Pt 17):3085-93.

Roth AD, Leisewitz AV, Jung JE, Cassina P, Barbeito L, Inestrosa NC, Bronfman M.
PPAR gamma activators induce growth arrest and process extension in B12 oligodendrocyte-like cells and terminal differentiation of cultured oligodendrocytes.
J Neurosci Res. 2003 May 15;72(4):425-35.

AÑO 2002

Brauer MM, Chavez-Genaro R, Richeri A, Viettro L, Frias AI, Burnstock G, Cowen T.  The oestrogenized rat myometrium inhibits organotypic sympathetic reinnervation. Auton Neurosci. 2002 Oct 31;101(1-2):13-22.

Cassina P, Peluffo H, Pehar M, Martinez-Palma L, Ressia A, Beckman JS, Estevez AG, Barbeito L. Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis. J Neurosci Res. 2002 Jan 1;67(1):21-9.

Chavez-Genaro R, Crutcher K, Viettro L, Richeri A, Coirolo N, Burnstock G, Cowen T, Brauer MM. Differential effects of oestrogen on developing and mature uterine sympathetic nerves. Cell Tissue Res. 2002 Apr;308(1):61-73. Epub 2002 Mar 08.

D'Albora H, Anesetti G, Lombide P, Dees WL, Ojeda SR.  Intrinsic neurons in the mammalian ovary. Microsc Res Tech. 2002 Dec 15;59(6):484-9. Review.

Estevez AG, Kamaid A, Thompson JA, Cornwell TL, Radi R, Barbeito L, Beckman JS.  Cyclic guanosine 5' monophosphate (GMP) prevents expression of neuronal nitric oxide synthase and apoptosis in motor neurons deprived of trophic factors in rats. Neurosci Lett. 2002 Jul 5;326(3):201-5.

Fernandez A, Radmilovich M, Trujillo-Cenoz O. Neurogenesis and gliogenesis in the spinal cord of turtles. J Comp Neurol. 2002 Nov 11;453(2):131-44.

Pehar M, Martinez-Palma L, Peluffo H, Kamaid A, Cassina P, Barbeito L. Peroxynitrite-induced cytotoxicity in cultured astrocytes is associated with morphological changes and increased nitrotyrosine immunoreactivity. Neurotox Res. 2002 Mar;4(2):87-93.

Richeri A, Viettro L, Chavez-Genaro R, Burnstock G, Cowen T, Brauer MM. Effects of infantile/prepubertal chronic estrogen treatment and chemical sympathectomy with guanethidine on developing cholinergic nerves of the rat uterus. J Histochem Cytochem. 2002 Jun;50(6):839-50.

Sapiro R, Kostetskii I, Olds-Clarke P, Gerton GL, Radice GL, Strauss III JF. Male infertility, impaired sperm motility, and hydrocephalus in mice deficient in sperm-associated antigen 6. Mol Cell Biol. 2002 Sep;22(17):6298-305.

Zhang Z, Sapiro R, Kapfhamer D, Bucan M, Bray J, Chennathukuzhi V, McNamara P, Curtis A, Zhang M, Blanchette-Mackie EJ, Strauss JF 3rd.  A sperm-associated WD repeat protein orthologous to Chlamydomonas PF20 associates with Spag6, the mammalian orthologue of Chlamydomonas PF16. Mol Cell Biol. 2002 Nov;22(22):7993-8004.

AÑO 2001

Anesetti G, Lombide P, D'Albora H, Ojeda SR.   Intrinsic neurons in the human ovary. Cell Tissue Res. 2001
Nov;306(2):231-7.  

Cassina P, Peluffo H, Barbeito L. Adaptative responses of spinal astrocytes to oxidative stress. Prog Brain Res. 2001;132:413-25. Review.

Cirillo A, Chifflet S, Villar B. Neural retina of chick embryo in organ culture: effects of blockade of growth factors by suramin. Cell Tissue Res. 2001 Jun;304(3):323-31.

AÑO 2000

Brauer MM, Chavez-Genaro R, Llodra J, Richeri A, Scorza MC. Effects of chronic oestrogen treatment are not selective for uterine noradrenaline-containing sympathetic nerves: a transplantation study. J Anat. 2000 Apr;196 ( Pt 3):347-55.

D'Albora H, Lombide P, Ojeda SR.  Intrinsic neurons in the rat ovary: an immunohistochemical study. Cell Tissue Res. 2000 Apr;300(1):47-56.

Sapiro R, Tarantino LM, Velazquez F, Kiriakidou M, Hecht NB, Bucan M, Strauss JF 3rd.  Sperm antigen 6 is the murine homologue of the Chlamydomonas reinhardtii central apparatus protein encoded by the PF16 locus. Biol Reprod. 2000 Mar;62(3):511-8.

AÑO 1999

Estevez AG, Spear N, Pelluffo H, Kamaid A, Barbeito L, Beckman JS.  Examining apoptosis in cultured cells after exposure to nitric oxide and peroxynitrite. Methods Enzymol. 1999;301:393-402. Review.

Vazquez C, Anesetti G, Martinez Palma L.  Transient expression of nitric oxide synthase in the hypoglossal nucleus of the rat during early postnatal development. Neurosci Lett. 1999 Nov 5;275(1):5-8.

AÑO 1998

Desdouits F, Siciliano JC, Nairn AC, Greengard P, Girault JA.  Dephosphorylation of Ser-137 in DARPP-32 by protein phosphatases 2A and 2C: different roles in vitro and in striatonigral neurons. Biochem J. 1998 Feb 15;330 ( Pt 1):211-6.
Fernandez A, Radmilovich M, Trujillo-Cenoz O. The marginal nuclei of the spinal cord in turtles: neuron assemblies in which gamma-aminobutyric acid and nitric oxide synthase are colocalized. Exp Brain Res. 1998 Sep;122(1):128-30.